Jay Dedrick, 37

"I couldn't convince myself to pursue a heavy-duty hangover, not even in the spirit of work duty and scientific experimentation. But having five or six beers in an evening can leave me with a mild headache the next morning, so I figured I could endure that much discomfort for the greater good. On night one, I had five 12-ounce beers during and after dinner; the low-grade headache arrived on schedule in the morning. On night two, I had a comparable meal and the same five beers, this time taking one two-tablet dose of RU-21 as I cracked open the first, third and fifth brews. Come morning, the headache was conspicuously - and welcomely - absent."

Penny Parker, 49

"After ingesting one RU-21 tablet after every two drinks (the instructions are confusing; I later noticed it's one serving - or two pills - for every two drinks), I woke up the next morning feeling fine, if not downright chipper. I admit, as a trained professional, I'm not prone to hangovers. But when I do get one, I get it with a vengeance - headache, nausea, lethargy. But with the help of RU-21, I felt like playing at least 18 holes of golf. Too bad I had to work. The bartender who assisted us in our experiment wants me to report back to him on the results. I'm saying yea, not nay, to RU-21."

Brian James, 30

"I thought I would put this stuff to the test by drinking microbrews, something I enjoy occasionally that can leave a mark on me if I have more than three. The first night, I drank five in about two hours - without the aid of the pills. I woke up the next morning with a light but noticeable headache and felt sluggish until about noon. The next night, I tried the pills. Their aftertaste was citrusy but complemented the beer nicely. I had the same five brews, then threw one more down for good measure. I woke up the next morning without any of the nagging aches or usual hangover effects. I was still slightly drowsy, but since the supplement doesn't claim to prevent that, I'll cut it some slack."